| Genetics |
GEN 804 - Genetics of Prokaryotic Microbes
Credits:
4.00
Expression and transfer of genetic elements (chromosomal
and nonchromosomal) in prokaryotic and eukaryotic
microorganisms; consideration of factors influencing public
health, industry, the environment, and society. Students
earning credit for PBIO 754/854; BCHM 854/854; GEN 754/854
may not receive credit for MICR 704/804. Prereq: general
mircobiology; biochemistry (Also offered as MICR 804.) Lab.
GEN 805 - Population Genetics
Credits:
4.00
An exploration of the forces affecting the frequency and
distribution of allelic variation in natural populations.
The relative role of mutation, selection, random drift, and
inbreeding in structuring genetic variation. Quantification
of the genetic structure of populations. Prereq: principles
of genetics; applied biostatistics I recommended. (Also
offered as ZOOL 805.) Special fee. (Not offered every year.)
GEN 806 - Human Genetics
Credits:
3.00
The genetic basis of human traits and diseases. New
understanding added by molecular genetic approaches. Human
genome project, gene therapy. Discussion of genetic
components of quantitative and behavioral traits in human
evolution. (Not offered every year.) (Also offered as ANSC
806.)
GEN 811 - Genomics and Bioinformatics
Credits:
4.00
The methods, applications, and implications of
genomics--the analysis of whole genomes. Microbial, plant
and animal genomics are addressed, as well as medical,
ethical and legal implications. The lab provides exposure
and experience of a range of bioinformatics approaches--the
computer applications used in genome analysis. Prereq:
Principles of Genetics. (Also offered as BCHM 811 and MICR
811.) Lab.
GEN 815 - Molecular Evolution
Credits:
4.00
Rates and patterns of evolutionary change in biomolecules.
Forces affecting the size and structure of genomes.
Molecular mechanisms of organismal evolution. Emphasis on
integrating evidence from biochemistry, molecular genetics
and organismal studies. Methods for reconstructing
phylogeny from molecular sequences. Prereq: principles of
genetics. Some knowledge of statistics and familiarity with
personal computers is recommended. (Also offered as ZOOL
815.) Special fee. Lab. (Not offered every year.)
GEN 823 - Quantitative Genetics
Credits:
4.00
Analysis of continuous variations in populations
simultaneously segregating at multiple loci. Genetic and
nongenetic factors and the complex interactions between
them. Models and methods of analysis for both theoretical
and practical applications. Prereq: principles of genetics;
applied biostatistics I, strongly suggested. (Also offered
as ZOOL 823.) Special fee. Lab. (Not offered every year.)
GEN 853 - Cytogenetics
Credits:
4.00
Chromosome structure, function, and evolution. Eukaryotic
genome organization. Theory of, and laboratory techniques
for, cytogenetic analysis in plants and animals. Prereq:
principles of genetics. (Also offered as PBIO 853.) Special
fee. Lab. (Not offered every year.)
GEN 854 - Laboratory in Biochemistry and Molecular Biology of Nucleic Acids
Credits:
5.00
Application of modern techniques to the analysis of
biomolecules, with an emphasis on nucleic acids; includes
DNA isolation and analysis, cloning, sequencing, and
analysis of gene products. No credit if credit has been
received for MICR 804. Prereq: BCHM 658/659; 751, or
permission. (Also offered as BCHM 854 and PBIO 854.)
Special fee. Not offered every year.
GEN 866 - Environmental Genomics
Credits:
4.00
The field environmental genomics uses existing and
developing high throughput genomic-scale technologies to
investigate ecological and evolutionary theory, and so
provides a more complete understanding of how organisms
respond to environmental change at the molecular genetic
level. Course covers an array of systems involved in this
emerging field, with the central aim of understanding the
effects of environmental change on genome structure, gene
expression, and adaptive evolutionary change. Information
is derived from the primary literature in the field and
covers practical and technical concepts as well as the
underlying theoretical basis for the major research themes.
Prereq: principles of genetics;/ or permission. (Also
offered as BCHM 866.)
GEN 871 - Molecular Genetics
Credits:
4.00
Structure, organization, replication, dynamics, and
expression of genetic information in eukaryotes. Focus on
molecular genetic mechanisms of gene expression and its
control; molecular genetics methods; molecular genetic
control of cell division and differentiation during
development. Prereq: a general biochemistry or principles
of biochemistry course; a course in principles of
genetics;/or permission. (Also offered as BCHM 871.)
GEN 872 - Evolutionary Genetics of Plants
Credits:
4.00
Mechanisms of genetic change in plant evolution,
domestication, breeding, and genetic engineering. Topics
include Darwinian theory; speciation and hybridization;
origins and co-evolution of nuclear and organelle genomes;
gene and genome evolution; transposable elements,
chromosome rearrangements, polypliody. Lab: DNA techniques,
sequence analysis programs, phylgenetic trees. Special fee.
Lab. Prereq: principles of genetics or equivalent;
introductory botany or principles of biology I and II or
equivalent. (Also offered as PBIO 872.) (Not offered every
year.)
GEN 874 - Plant Biotechnology and Genetic Engineering
Credits:
3.00
Plant transformation and regeneration, gene isolation and
identification, structure and regulation of plant genes,
current applications of plant genetic engineering,
environmental and social implications. Prereq: BIOL 604 or
permission. (Also offered as PBIO 874.)
GEN 875 - Plant Biotechnology and Genetic Engineering Lab
Credits:
2.00
Techniques for genetic transformation and selection of
plants, analysis of foreign gene expression, and plant
cell and tissue culture. Coreq: PBIO or GEN 874. (Also
offered as PBIO 875.) Special fee. (Not offered every year.)
Co-requisites:
GEN 874
GEN 882 - Developmental Genetics
Credits:
3.00
The molecular genetic basis of metazoan development.
Focuses on how genes direct the process of development and
how this problem is analyzed in model organisms using
molecular approaches. Topics include: control of cell
division, maternal factors, cell-cell interactions, and
differential gene expression. Prereq: principles of
genetics; general biochemistry; BCHM 851. (Also offered as
BCHM 882.)
GEN 895 - Special Topics
Credits:
2.00 to 4.00
GEN 899 - Master's Thesis
Credits:
1.00 to 10.00
Cr/F.
GEN 995 - Special Topics
Credits:
2.00 to 4.00
Intended for study in specialty areas not ordinarily
included in other courses. May involve formal classes,
discussions, or independent investigations. Prereq:
permission.
GEN 996 - Special Topics
Credits:
2.00 to 4.00
See description for GEN 995.
GEN 998 - Genetics Seminar
Credits:
1.00
Presentation and discussion of selected genetic topics.
May be repeated. Cr/F.
GEN 999 - Doctoral Research
Credits:
Cr/F.