| Microbiology |
MICR 800 - Pathogenic Microbiology
Credits:
5.00
Morphologic, cultural, biochemical, serologic,
epidemiologic, and pathogenic characteristics of
microorganisms causing human and animal diseases. Discussion
of clincial presentations in host and laboratory diagnoses
and treatment measures. Prereq: general microbiology.
Special fee. Lab.
MICR #802 - Infectious Disease and Health
Credits:
5.00
Principles underlying the nature of infectious agents and
the diseases they cause. Pathogenic strategies employed by
these microorganisms, response of the host at the animal and
cellular levels, intracellular parasitism, epidemiology,
role of control measures including vaccines and
chemotherapy, mode of action of antimicrobial
chemotherapeutic agents, pharmacokinetics, and drug
metabolism. Both well-established pathogens as well as newer
and emerging human and animal disease agents are covered.
Prereq: pathogenic microbiology; permission. Special fee.
Lab.
MICR 804 - Genetics Prokaryotic Microbes
Credits:
4.00
Expression and transfer of genetic elements (chromosomal and
nonchromosomal) in prokaryotic and eukaryotic
microorganisms; consideration of factors influencing public
health, industry, the environment, and society. Students
earning credit for PBIO 754/854; BCHM 754/854;
GEN 754/854 may not receive credit for GEN 704/804.
Prereq: general microbiology; biochemistry (Also offered as
GEN 804.) Special fee. Lab.
MICR 805 - Immunology
Credits:
5.00
Introduction to the major cellular and molecular components
of the immune system; examination of their development wand
production, their interactions with each other and with
other systems in the body, and their regulation; exploration
of their role in beneficial and harmful immune responses in
humans and animals. Prereq: general microbiology. Special
fee. Lab.
MICR 806 - Virology
Credits:
3.00
Principles of animal and, in selected instances, plant and
bacterial virology in relation to infection and disease.
Emphasis on the molecular biology of viruses, viral
replication, isolation, propagation, assay, pathogenesis,
diagnosis, detection, epidemiology, and control. Prereq:
general microbiology.
MICR 807 - Marine Microbiology
Credits:
3.00
Qualitative and quantitative evaluation of the physiological
activities of microorganisms that influence the state of
carbon, nitrogen, sulfur, iron, manganese, phosphorous,
hydrogen, oxygen, and other elements in the sea and its
sediments. Provides an understanding of the
interrelationships between marine microorganisms and
their surroundings by integrating microbiological phenomena
with known aspects of physical, chemical, and biological
oceanography. Introduces students to the primary scientific
literature in marine microbiology, teaches each student how
to think provocatively and concertedly, and convey those
thoughts clearly and concisely in both oral and written
form. Prereq: general microbiology.
MICR 808 - Virology Lab
Credits:
2.00
Principles and practices of animal, selected plants, and
bacterial virological methods for the propagation,
detection, and enumeration of viruses. Prereq: general
microbiology. Coreq: virology. Special fee.
Co-requisites:
MICR 806
MICR #810 - Electron Microscopy and Microbial Cytology
Credits:
3.00
Ultrastructure of eukaryotes, prokaryotes, and viruses. Role
of bacterial appendages; cell membranes and cell walls;
cytoplasmic inclusions; cell division and sporulation and
virus ultrastructure. Preparative electron microscopy
techniques for biological material (and microorganisms)
described in detail. Prereq: general microbiology;
permission. (Not offered every year.)
MICR 811 - Genetics of Eukaryotic Microbes
Credits:
4.00
Expression and transfer of genetic material in eukaryotic
microbes including fungi, algae, protozoa, and
Caenorhabditis elegans. Laboratory experience in DNA
sequence entry retrieval and analysis. Macintosh
workstations are used for accessing and retrieving data from
the National Laboratory of Medicine and other sources via
the Internet. Prereq: general microbiology; principles of
genetics. (Also offered as BCHM 811 and GEN 811.) Lab.
MICR #812 - Electron Microscopy Laboratory
Credits:
3.00
Operation of electron microscopes; manipulation of
instrumentation and specimens. Application of shadowing,
negative staining, embedding, thin-sectioning, labeling,
freeze-fracture/etching to biological specimens;
photographic techniques; interpretation of micrographs.
Project work. Prereq: general microbiology; Coreq:
MICR 810; permission. Special fee. (Not offered every year.)
Co-requisites:
MICR 810
MICR 813 - Microbes and the Environment
Credits:
5.00
Physiological ecology as required to understand the roles of
microbes in matter and energy flow through ecosystems.
Structure and function of aquatic, terrestrial and biotic
habitats in which microbes are important, including life in
biofilms. Consideration is given to (micro)biotic community
interactions, including systrophy, consortial mixtures and
stable symbioses between prokaryotes and eukaryotes.
Lab provides experience with methods of evaluating
composition, structure and activity of microbial communities
including extraction of nucleic acids from the environment
and ecological use of oligonucleotide probes. An important
facet of both lab and lecture includes biochemistry of and
enrichment, isolation; and enumeration methods for
physiological groups of aerobic and anaerobic microbes
(such as denitrifiers, sulfate reducers, metal reducers,
homoacetogens, celluloytics, nitrogen fixers, diverse
extrameophiles and autotrops including nitrifyers,
methnanogens, and photosymtherics). Prereq: general
microbiology. Special fee. Lab.
Co-requisites:
MICR 814 - Water Pollution Microbiology
Credits:
4.00
MICR 817 - Microbial Physiology
Credits:
5.00
Fundamental physiological and metabolic processes of
bacteria and fungi with a strong emphasis on prokaryotes.
Literature-based course. Topics include regulation and
coordination of microbial metabolism, bacterial cell cycle,
function of prokaryotic cell structure, diversity of energy
metabolism, and microbial cell differentiation. Prereq:
general microbiology; general biochemistry; permission.
Special fee. Lab.
MICR 818 - Ethics and Issues in Microbiology
Credits:
3.00
In conjunction with advances being made in the biological
sciences is the need for scientific integrity. From guiding
students in the laboratory to scientific record keeping,
from authorship and peer review to potential conflicts of
interest, from use of animals and humans in research to
genetic technology, scientists need to understand the
ethical issues that underlie their work. These and related
issues will be presented and discussed in a format that
encourages both an appreciation of established guidelines
and an opportunity to critically examine them. (Not offered
every year.)
MICR 819 - Prokaryote Biodiversity
Credits:
5.00
By what means can we evaluate the composition and diversity
of the prokaryotic world? What are the molecular techniques
which have provided new ways of collecting taxonomic and
phylogenetic data and of evaluating the evolutionary history
of prokaryotes? How can we use molecular methodologies
epidemiologically to track the distribution of particular
strains of microorganisms? What characteristics distinguish
each fascinating group of (known) prokaryotes? In addition
to exploring these topics, students in this course will
isolate new strains of microbes and will proceed to identify
and characterize them by molecular and other methods. The
laboratory will also enable students to learn how to examine
natural habitats for the presence of particular prokaryotic
groups in the absence of cultivating their representatives.
Prereq: general microbiology. Special fee. Lab.
MICR 851 - Cell Culture
Credits:
5.00
Principles and technical skills fundamental to the culture
of animal and plant cells, tissues and organs. Introduction
to the techniques of subculturing, establishing primary
cultures, karyotyping, serum testing, cloning, growth
curves, cryopreservation, hybridoma formation and monoclonal
antibody production, and organ cultures. An
interdisciplinary course with emphasis on the application of
cell culture to contemporary research in the biological
sciences. Prereq: general microbiology; permission. (Also
offered as ANSC 851 and PBIO 851.) Special fee. Lab.
MICR #852 - Mammalian Cell Culture
Credits:
5.00
Basic concepts and techniques associated with the
cultivation of mammalian cells in vitro, including media
preparation, cell viability, transfer, cloning,
crypopreservation; use of transformed cells harboring
cloning vectors for production of bioproducts. (No credit
if already taken MICR 851.) Prereq: general microbiology.
(Also offered as ANSC 852.) Special fee. Lab.
MICR 866 - Plant-Microbe Interactions
Credits:
3.00
Physical, chemical, genetic and molecular methods utilized
by plant pathogens (bacteria, fungi, and viruses) will be
discussed, as will beneficial plant-microbe symbioses.
Prereq: principles of biology, general microbiology or
permission. (Also offered as PBIO 866.)
MICR 893 - Advanced Problems and Techniques in Microbial Cytology
Credits:
1.00 to 4.00
Research with electron microscopy. Includes reading,
organized seminars in microbial cytology, recent advances in
electron microscopy, and laboratory project work. Prereq:
MICR 810; permission. May be repeated to a maximum of
8 credits.
MICR 895 - Special Topics in Microbiology
Credits:
1.00 to 4.00
Advanced studies in specific areas. Prereq: permission.
May be repeated to a maximum of 8 credits.
MICR 899 - Master's Thesis
Credits:
1.00 to 10.00
Credit/Fail.
MICR #904 - Advanced Microbial Genetics
Credits:
4.00
Advanced studies in expression, regulation, recombination,
and transmission of genetic information in prokaryotic
microorganisms. Prereq: MICR 804; permission. (Also offered
as GEN 904.) Special fee. Lab. (Not offered every year.)
MICR 905 - Current Topics in Microbiology
Credits:
1.00
Discussion of current developments in microbiology:
A) Microbial Ecology; B) Immunology; C) Pathogenic
Mechanisms; D) Microbial Genetics; E) Water-borne Diseases;
F) Microbial Physiology. May be repeated.
MICR 906 - Hot Topics in Microbiology
Credits:
1.00
Presentation and discussion of current literature in
Microbiology. Required of all Microbiology graduate
students. May be repeated.
MICR 907 - Instrumentation
Credits:
1.00
Introduction top safety and principles of use in
instrumentation in microbiology. May be repeated to a
maximum of 5 credits. Credit/Fail.
MICR 909 - Advanced Virology
Credits:
4.00
Provides in-depth study of virology. Selected RNA, DNA,
retroviruses, and nonretroviruses capable of causing cancer.
Enables students to (1) understand genetic regulatory events
occurring during virus-cell interactions, and to
(2) understand the specific pathogenicity, epidemiology,
prevention, and control of selected (model) viruses. Prereq:
virology; permission. Special fee. Lab. (Not offered every
year.)
MICR 997 - Microbiology Seminar
Credits:
1.00
Presentation and discussion of selected topics in
microbiology. Required of all graduate students in
microbiology. May be repeated. Credit/Fail.
MICR 999 - Doctoral Research
Credits: